12/case directions: brush teeth thoroughly after meals, at least twice a day or as directed by your dental professional or physician. Periobrite is concentrated - use a pea size amount. Do not swallow. For children 2-6 years of age, supervise use until good habits are established. For children under 2 years of age, consult your dental professional or physician. Ingredients: calcium carbonate, glycerin, water, sodium bicarbonate, natural flavor, cellulose gum, bio-saponins(r) (yucca schidigera root extract, quillaja saponaria root extract, dioscorea villosa (wild yam) tuber extract, smilax regelii root extract), xylitol, mentha piperita (peppermint) oil, *** xanthan, calendula officinalis flower extract, echinacea purpurea flower/leaf/stem extract, chamomilla recutita (matricaria) flower extract, centella asiatica extract, zanthoxylum americanum bark extract, origanum vulgare leaf extract, quillaja saponaria root extract, lavandula angustifolia (lavender) oil, syzygium aromaticum (clove) bud oil, folic acid, olea europaea (olive) leaf extract, thymus vulgaris (thyme) flower/leaf oil, eucalyptus globulus leaf oil, phytoplenolin(r) (centipeda cunninghamii herb extract), cinnamomum zeylanicum bark oil, citrus grandis (grapefruit) seed extract, juglans nigra (black walnut) shell extract, ubiquinone (coq10), camellia sinensis (green tea) leaf extract, aloe barbadensis leaf juice. (r)-trademarks of bio-botanica(r) 12/19/16