12/case directions: for adults, take one (1) tablet daily, with or without food, or as recommended by a nutritionally-informed physician. Serving size: one (1) tablet ingredients: methylsulfonylmethane (msm) 1500 mg other ingredients: microcrystalline cellulose, stearic acid, modified cellulose (coating), magnesium stearate (vegetable source). Non-gmo and gluten free. 04/20/17