12/case directions: use in place of toothpaste or as directed by your health care professional. (wet toothbrush, dip toothbrush in herbal toothpowder, then use in place of toothpaste.) for optimum results: use the same as toothpaste. Use at least two to three times a day. Ingredients: proprietary blend: one toothbrush full organic shavegrass herb, organic peppermint leaf, wildcrafted white oak bark, organic cloves, wildcrafted prickly ash bark, wildcrafted bayberry bark, wildcrafted slippery elm bark & organic stevia herb. Other ingredients: none. No added fillers or chemicals. 02/09/17