60/case directions: 1. Remove your denture and brush it under running water with a toothbrush. 2. drop one cleaning tablet into enough warm water to cover denture or appliance. Place denture into effervescing solution. 3. leave your denture or appliance in the solution for 30 minutes to completely remove all invisible water insoluble residues. For best results, use once a day. Your denture may be safely soaked overnight. 4. remove and rinse denture or appliance under running water. Dry thoroughly before applying secure denture bonding cream or secure denture adhesive cushions. 02/02/12